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We sincerely thank all participating institutions for their valuable contribution to the REGYS project, a retrospective study focused on rare gynecological sarcomas, which has so far resulted in five publications — three in Q1 journals and two in Q2 journals.

In addition, at least two further publications, focusing on MTAP deletion and on an mRNA expression profile classifier, are currently in preparation and will also be co-authored by all participating institutions.

Given the uniqueness of the collected samples, we are now preparing a follow-up project: REGYS-2. Details of the new REGYS-2 project will be shared soon, along with an invitation to participate. We sincerely hope for your continued collaboration.

Publications co-authored by all participating institutions:

1.     Dundr P, et al. The Rare Gynecologic Sarcoma Study: Molecular and Clinicopathologic Results of A Project on 379 Uterine Sarcomas. Lab Invest. 2025 May;105(5):104092. doi: 10.1016/j.labinv.2025.104092

2.     Hojný J, et al. Decoding the Molecular Landscape of 262 Uterine Sarcomas: RNA-Seq Clustering of ESS, UTROSCT, and UUS with Prognostic Insights. Lab Invest. 2025 May 24:104198. doi: 10.1016/j.labinv.2025.104198

3.     Flídrová M, et al. Immunohistochemical analysis of 147 cases of low-grade endometrial stromal sarcoma: refining the immunohistochemical profile of LG-ESS on a large, molecularly confirmed series. Virchows Arch. 2025 Jan 21. doi: 10.1007/s00428-025-04026-4

Publications co-authored by contributing institutions only:

1.     Dundr P, et al. Uterine sarcoma with KAT6B/A::KANSL1 fusion: a molecular and clinicopathological study on 9 cases. Virchows Arch. 2025 Mar;486(3):551-562. doi: 10.1007/s00428-024-03994-3

2.     Flídrová M, et al. Unraveling the Molecular Landscape of Uterine Tumor Resembling Ovarian Sex Cord Tumor: Insights From A Clinicopathological, Morphologic, Immunohistochemical, and Molecular Analysis of 35 Cases. Mod Pathol. 2024 Dec;37(12):100611. doi: 10.1016/j.modpat.2024.100611

We look forward to continuing this important collaboration in the upcoming REGYS-2 project.

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The State-of-the-Art Conference on Gynecology and Oncology is fast approaching! As a reminder, the conference will take place on September 29–30, 2025, in Prague.

If you have not registered yet, please do so as soon as possible at www.sago-conference.eu.

We look forward to seeing you in Prague, catching up in person, and sharing an inspiring programme together!

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Final outcome paper of the SENTIX study published in Nature Cancer!

We are pleased to share the latest publication from the ENGOT-Cx2/CEEGOG CX-01/SENTIX academic surgical trial, now published in Nature Cancer.

This prospective, single-arm, international trial evaluated the safety of sentinel lymph node biopsy without systematic pelvic lymphadenectomy in patients with early-stage cervical cancer. The final survival outcomes provide valuable evidence to inform both clinical practice and future research.

Notably, half of the patients enrolled in the SENTIX study came from CEEGOG sites. We sincerely thank all participating sites and collaborators for their invaluable contribution.

📄 Read the full article here: https://www.nature.com/articles/s43018-025-01016-y#citeas

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The CEEGOG representatives for the upcoming GCIG 7th Ovarian Cancer Consensus Conference – Clinical Research, to be held on April 30 – May 1, 2026, in Toronto, Canada, have been selected recently.

Following a thorough review by the CEEGOG Scientific Committee, the following physicians have been chosen as our nominees:

David Cibula – Gynaecological Oncology

Filip Frühauf – Diagnostics, Gynaecological Oncology

Lika Katselashvili – Medical Oncology

Marija Živković Radojević – Radiation Oncology

In line with GCIG guidelines, each GCIG group may nominate up to four delegates, from which the OCCC-CR Executive Committee will select two final participants to ensure balanced representation of disciplines across all topic groups.

We sincerely thank all applicants for their interest in representing CEEGOG and for their ongoing commitment to advancing collaborative international research in gynaecologic oncology.

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We are pleased to announce that the final results of the CEEGOG EX-02 / TESLA-1 study have been published in the journal Cancers.

TESLA-1 was a prospective observational study in patients with early-stage endometrial cancer, comparing two concurrent sentinel lymph node (SLN) labelling techniques: a radioactive tracer (with or without blue dye) versus indocyanine green (ICG). The primary objective was to evaluate and compare the SLN detection rate between these two intracervical tracer methods.

We sincerely thank all participating sites for their valuable cooperation. It was a great pleasure to work with you on this study!

📄 Read the full article here: https://www.mdpi.com/2072-6694/17/10/1606

  1. GCIG Spring Meeting – Chicago, May 28–29, 2025
  2. CEEGOG Annual Meeting 2025 – Key Highlights
  3. New Publication from CEEGOG CX-07 / RECER Study
  4. ENGOT meeting in NICE, April 3 – 4, 2025